![]() ![]() ![]() ![]() Here, we generated functionally mature SC-islets using an optimized protocol and benchmarked them comprehensively against primary adult islets. Despite progress in the generation of stem-cell-derived islets (SC-islets), no detailed characterization of their functional properties has been conducted. Transplantation of pancreatic islet cells derived from human pluripotent stem cells is a promising treatment for diabetes. Nature Biotechnology volume 40, pages 1042–1055 ( 2022) Cite this article Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells ![]()
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